Objective: To investigate the density and disperse significance of the lymphatic in squamous cell carcinoma of the esophagus and its relation with lymph node metastasis. Methods: Monoclonal antibody D2- 40 was used immunohistochemically to detect the lymphatic vessel density( LVD) in the intra and peri- tumoral areas and normal tissue of the esophagus. Results: LVD of the peri- tumoral area was significantly higher than intra- tumoral area and nomal tissue( P < 0. 01). LVD of the peri- tumoral area was sign...
【基金】
国家自然科学基金(编号:81071737)
【更新日期】
2015-01-06
【分类号】
R735.1
【正文快照】
Modern Oncology 2014,22(12):2897-2899【修回日期】2014-06-13单克隆抗体D2-40检测食管癌巢周围和癌巢中心区以及正常食管组织中淋巴管密度(LVD),分析其与临床病理因素的关系。结果:癌巢周围区LVD明显高于中心区和正常组织(P<0.01)。癌巢周围区LVD与淋巴结转移及分化程度相关