Traditional radiotherapy,chemotherapy and operation treatment has the disadvantages of low ability about anti tumor,anti index is too small,the side effects are easy develop,most often lack the right treatment,therefore,biological treatment method has become a focus of attention in the field of cancer therapy. Gene virus therapy- is one of them,can achieve the purpose of treatment and prevention of tumor. This paper will review this therapy progression.
【更新日期】
2014-11-11
【分类号】
R73-36
【正文快照】
Modern Oncology 2014,22(10):2499-2502腺病毒载体目前广泛地应用于肿瘤的基因治疗。随着对腺病毒分子结构、功能以及感染机制的进一步深入了解,在降低其免疫原性、增强基因导入特异性、增强感染和表达效率等方面进行了探索,具有肿瘤靶向性的溶瘤腺病毒载体是其发展方向与研究