【摘要】 NDRG2属于NDRG家族(N-myc down-stream regulated gene family),是一种与细胞增殖和分化相关的抑癌基因,分布广泛且生物学功能复杂,在全身多种组织器官均有表达。参与组织胚胎发育、细胞分化并且与血液免疫系统关系密切。在缺血再灌注损伤中对组织起保护作用。与肿瘤的发生、发展和转归密切相关。本文就NDRG2最近研究进展作一综述。更多还原

【Abstract】 DRG2 belongs to the NDRG family(N-myc down-stream regulated gene family),is a kind of cell proliferation and differentiation related genes,which widely distributed and has complex biological functions.It is expressed in various organs and tissues,involved in embryonic development,cell differentiation,closely related with the blood immune system,playing the role of protective effects on tissue in ischemia reperfusion injury.Recently,it is found that NDRG2 is closely related to tumorigenesis,development,tumor metastasis and prognosis.This review will discuss the progress research on NDRG2.更多还原