【摘要】 目的:探讨晚期不可手术的IV期恶性肿瘤患者合并恶性肠梗阻(MBO)的预后因素。方法:选取70例随访资料完整的合并MBO的晚期肿瘤患者,并记录患者的人口统计学、临床特点、实验室检查、影像学检查及ECOG评分等特征。随访结束至2012年12月。单因素生存分析采用Kaplan-Meier生存曲线,多因素分析采用COX比例风险回归模型。结果:是否伴有腹膜转移和腹水、梗阻部位、ECOG评分、白蛋白水平、MBO诊断后治疗模式(后续治疗vs支持治疗)均可影响MBO患者的预后,但仅ECOG评分、MBO诊断后治疗模式可作为影响MBO患者预后的独立危险因素。结论:MBO受各种因素影响。更多还原

【Abstract】 Objective: To investigate the prognostic factors in patients with non- curative stage IV cancer and malignant bowel obstruction( MBO). Methods: All 70 cases of MBO patients with complete follow- up data were collected into the study. Demographic,clinical,laboratory,radiographic information and the patient’s functional status( Eastern Cooperative Oncology Group score,ECOG) were recorded. Follow- up was until death or the end of the study( December 2012). Survival was estimated using Kaplan- Meier plots and COX regression models were used to evaluate prognostic factors for survival. Results: Carcinomatosis,ascites,ECOG performance status,obstructive site,albumin level,and post- incident treatment model were correlated to the prognosis of MBO,but only ECOG performance status and post- incident treatment model were the independent prognostic indicators. Conclusion: MBO is influenced by meltifactors.更多还原