【摘要】 目的 分析急性白血病免疫分型的特点,为临床诊断提供快速准确的实验室依据。方法 回顾93例初发急性白血病的临床资料,采用流式细胞术进行骨髓免疫分型。结果 93例初发急性白血病中,急性髓系白血病(AML)66例,其抗原表达从低到高依次为:CD7(16.7%),CD15(30.3%),CD71(31.2%),CD11B(34.5%),CD34(48.5%),CD117(50.0%),HLA-DR(65.2%),CD13(70%),CD33(86.4%)和CD38(92.4%)。急性B淋巴细胞白血病(B-ALL)22例,其抗原表达从低到高依次为:CD34(36.4%),CD20(50.0%),CD38(63.6%),CD10(72.7%),HLA-DR(86.3%)和CD19(95.5%)。急性T(T-ALL)淋巴细胞白血病5例,其抗原表达从低到高依次为:HLA-DR(60.0%),CD34(60.0%),CD2(80.0%),CD7(80.0%)和CD38(100.0%)。结论 流式细胞术免疫分型能够快速、准确地为临床急性白血病的分型诊断提供依据。更多还原

【Abstract】 Objective To analyse the immunophneotype features of acute leukemia provides fast and accurate laboratory basis for clinical diagnosis(FCM).Methods Reviewed the clinical data of 93 cases with the first occurrence of acute leukemia,bone marrow immune classification using flow cytometry.Results In 93 cases,acute myeloid leukemia(AMD accounts for66 cases,the antigen expression in turn from low to high was:CD7(16.7%),CD15(30.3%),CD71(31.2%),CD11B(34.5%),CD34(48.5%),CD117(50.0%),HLA-DR(65.2%),CD13(70%),CD33(86.4%) and CD38(92.4%).22 cases were acute B lymphocytic leukemia(B-ALL) and the antigen expression in turn from low to high was:CD34(36.4%),CD20(50.0%),CD38(63.6%),CD10(72.67%),HLA-DR(86.3%) and CD19(95.5%).Acute T lymphocyte leukemia(TALL) accounts for 5 cases,the antigen expression in turn from low to high was:CD34(60.0%),HLA-DR(60.0%),CD2(80.0%),CD7(80.0%) and CD38(100.0%).Conclusion FCM immune classification would be able to quickly and accurately provide the basis for clinical diagnosis classification of acute leukemia.更多还原