Objective: This study aimed to examine the immune-regulatory effect and acute toxicity of Agaricus blazei polysaccharide in mice. Methods: The effects of Agaricus blazei polysaccharide on immunological organs in mice and the ability of the reticuloendothelial system to clear inert carbon particles from bloodstream were observed in order to explore the immunoregulatory effect on mammals. By using an improved Karber's method, the acute toxicity of Agaricus blazei polysaccharide was studied. Results: Agaricus ...