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影响主动脉平滑肌细胞迁移的因素
Infl uencing factors of vascular smooth muscle cell migration
【摘要】 平滑肌细胞(vascular smooth muscle cell,VSMC)的迁移对血管发育、动脉粥样硬化和术后再狭窄等起到关键性的作用。主要从激发VSMC迁移的关键炎性细胞因子、细胞间相互作用的核心成员、microRNA、细胞骨架和上述各因素的迁移信号通路这几方面来综述VSMC的迁移。
【Abstract】 The migration of vascular smooth muscle cell(VSMC) plays a key role in vascular development, atherogenesis and restenosis. Here, we review recent progresses made toward the key inflamm atory cytokines triggerring VSMC migration, key players between cell-matrix and cell-cell contacts, microRNA, cytoskeleton and signaling pathway events of each factor mediating VSMC migration, which are characteristics as infl uence factors of VSMC migration.
【基金】 山东省中青年科学家科研奖励基金计划项目(BS2011SW049)
- 【文献出处】 生命科学 ,Chinese Bulletin of Life Sciences , 编辑部邮箱 ,2014年07期
- 【分类号】R329.2
- 【被引频次】2
- 【下载频次】99