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蓝光联合茵栀黄颗粒治疗新生儿病理性黄疸临床疗效分析

Analysis the clinical efficacy of blu-ray combined with Yinzhihuang Keli for newborn pathological jaundice

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【作者】 李举郝晓广

【Author】 LI Ju;HAO Xiao-guang;Department of New Pediatric,People’s Hospital in Pingyi county of Shandong Province;Department of Surgery,People’s Hospital in Pingyi county of Shandong Province;

【机构】 山东省平邑县人民医院新生儿科山东省平邑县人民医院外科

【摘要】 目的蓝光联合茵栀黄颗粒治疗新生儿病理性黄疸,研究其临床疗效并对其安全性作出评价。方法 1 20例新生儿黄疸病例随机分为两组,即治疗组与对照组,每组60例。对照组患儿采用传统治疗:服用酶诱导剂苯巴比妥;每日连续蓝光照射8 h。治疗组在传统治疗基础上,口服茵栀黄颗粒。7 d为1个疗程,1个疗程后观察2组疗效。结果与对照组相比,在1个疗程的治疗过程中,蓝光联合茵栀黄颗粒治疗新生儿黄疸,血清胆红素下降速度更快(P<0.01),下降程度更大(P<0.01),平均退黄时间明显缩短(P<0.01);蓝光联合茵栀黄颗粒治疗新生儿黄疸总有效率为98.33%,对照组总有效率为91.67%,治疗组治疗效果优于对照组,有显著性差异(P<0.05)。结论与传统治疗方法相比,联合应用蓝光联合茵栀黄颗粒治疗效果明显提高,退黄速度快,不良反应小,值得临床推广。

【Abstract】 Objective To analysis the clinical efficacy of blue-ray combined with Yinzhihuang Keli for newborn pathological jaundice.Method120 newborns with neonatal jaundice were randomly divided into control group(traditional treatment group,took enzyme inducers phenobarbital and continuous blue-ray radiation for 8 h everyday) 60 cases and treatment group(Yinzhihuang Keli combined with traditional treatment group) 60cases,7 days for a course of treatment,then the efficacy of two groups were compared.Results After 7 days treatment,we found compared with control group,the speed of decline of serum bilirubin of treatment group was much faster,the degree of decline was much bigger and the average time of jaundice subside was much shorter,all P<0.05.The total efficiency of treatment group was 98.33%which was significantly higher than the control group which was 91.67%,P<0.05.Conclusion Compared with conventional treatment methods,blue-ray combined with Yinzhihuang Keli for neonatal jaundice would get a better efficacy,faster speed of jaundice subside and smaller side effects.

  • 【分类号】R722.17
  • 【被引频次】44
  • 【下载频次】201
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