【摘要】 目的 利用小动物CT(micro-CT)收集正常雌性BALB/c-nu/nu小鼠与BALB/c小鼠股骨的影像学数据。方法 BALB/c-nu/nu小鼠与BALB/c小鼠各15只，雌性，10～12周龄，取股骨后用micro-CT进行扫描，将得到的数据进行系统分析。结果 成功收集了正常雌性BALB/c-nu/nu小鼠与BALB/c小鼠股骨的CT影像学数据。通过数据分析，发现两者在皮质骨相对骨体积上具有显著差异,在骨小梁相对骨体积、骨表面积与组织体积比值和骨密度也有显著差异。结论 micro-CT可以对雌性小鼠股骨的各项参数进行定量分析。更多还原

【Abstract】 Objective To obtain femur bone datas about female BALB/c-nu/nu and BALB/c mice by using micro-CT. Methods The femur from fifteen female nude mice with BALB/c background and BALB/c mice respectively, aged 10-12weeks, were scanned with micro-CT. Results The parameters of female BALB/c-nu/nu and BALB/c mice femur bone were detected by using micro-CT, there are differences of femur bone in some parameters between BALB/c-nu/nu and BALB/c mice. In the vortical bone, there is significant difference in BV/TV.In the trabecular bone, BV/TV, BS/TV and BMD have significant difference. Conclusions Micro-CT can be used for quantitative analysis of mice femur bone parameters.更多还原