【摘要】 目的:分析子宫中隔长度及基底宽度对妊娠的影响,探讨宫腔镜手术治疗不同状态中隔子宫的临床疗效。方法:回顾性分析行宫腔镜子宫中隔切除术(TCRS)并有生育要求的随访资料完整的75例中隔子宫患者的临床资料,按中隔长度与宫深的关系<1/3、1/3~2/3、≥2/3分为3组,按中隔基底宽度<1 cm、≥1 cm分为两组,分别比较手术前后自然流产率及活产率。结果:中隔长度<1/3组、1/3~2/3组、≥2/3 3组间自然流产率分别为55.56%、88.00%和90.00%,差异有统计学意义(P<0.05);子宫中隔长度≥1/3的自然流产率(120/135,88.89%)显著高于中隔长度<1/3者;术后与术前比较,3组的自然流产率均显著降低,活产率均显著升高,差异均有统计学意义(P<0.05)。中隔基底宽度≥1 cm者其自然流产率显著高于<1 cm者(88.39%vs 69.49%),活产率低于<1 cm者(10.71%vs 27.12%);手术后患者的自然流产率降低,活产率升高,差异有统计学意义(P<0.05)。不同状态中隔子宫在行TCRS术后自然流产率、活产率组间比较,差异均无统计学意义(P>0.05)。结论:子宫中隔长度达到宫腔深度1/3或基底宽度达到1 cm会显著增加自然流产率。TCRS术可明显改善妊娠结局,术前中隔子宫状态对术后妊娠结局无影响。更多还原

【Abstract】 Objective: To analyze the influence of length and basal width of uterine septum on pregnancy outcome,and the clinical efficacy of hysteroscopic resection on uterine septum. Methods: 75 patients of uterus septum with birth demand and complete follow-up data were enrolled in this analysis,who were assigned into three groups according to the septum length( <1 /3,1 /3-2 /3,and≥2 /3),and two groups according to the basal width( <1 cm and≥1 cm). The miscarriage and live birth rates were compared among groups. Results:The miscarriage rate was 55. 56%,88. 00% and 90. 00% in the group of septum length <1 /3,1 /3-2 /3,and≥2 /3,respectively( P <0. 05). The miscarriage rate was 88. 39% and 69. 49% in the group of basal width≥ 1 cm and<1 cm miscarriage. The miscarriage rate significantly decreased and live birth rate increased after surgery. Conclusions: The miscarriage rate significantly increased in patient with uterine septal length over1 /3 or basal width≥1 cm. Hysteroscopic resection can significantly improve the pregnancy outcome,and the preoperative septum conditions have no effect on the pregnancy outcome.更多还原