Objective To explore the effects of streptozotocin(STZ)-induced diabetes combined with chow diet on atherosclerotic lesions of apoE-/- mice. Methods After 2 weeks of chow diet,60 male apoE-/- mice(10 weeks old)were randomly divided into two groups. Diabetic apoE-/-mice(n = 30) were constructed by intraperitoneal injection of low-dose STZ for 5 consecutive days. ApoE-/- mice(n = 30) injected with citrate buffer liquid served as non-diabetic controls. All mice were fed with chow diet until sacrifice(23 weeks ...