Objective To analyze the changes of plasma D-dimer level in breast cancer patients,and to investigate the relationship between the level of D-dimer and prognosis of breast cancer. Methods A total of 92 cases of primary breast cancer and 85 healthy controls were enrolled. The level of D-dimer was measured with latex-enhanced immunoassay,and ER,PR,HER2,Ki-67 and P53 levels were detected with immunohistochemical methods. During the follow-up of 8 months,the plasma D-dimer levels in breast cancer patients were ...