【摘要】 目的结合后循环影像学评估,探讨早期评价急性后循环脑梗死(PCI)患者结局的相关因子。方法收集收住神经重症监护室(NICU)的PCI患者78例。回顾性分析其基线的Glasgow昏迷评分(GCS)、后循环-ASPECTS影像评分及病情进展与90 d的改良Rankin评分(mRS)评估结局的相关性。结果相对于后循环-ASPECTS评分≥8分者,评分<8分者的基线的国立卫生院卒中量表(NIHSS)评分高、GCS评分低及结局差。患者90 d的mRS与基线GCS评分(P=0.018)、后循环-ASPECTS评分(P=0.001)及病情进展(P=0.001)相关。结论急性PCI患者,基线GCS评分≤8分、后循环-ASPECTS评分<8分及发生病情进展均预示结局不良。更多还原

【Abstract】 Objective To explore the outcome predictors in the early stage of acute posterior circulation ischemic( PCI) stroke by combination of clinical data and the posterior circulation Alberta Stroke Program Early CT Score( pc-ASPECTS). Methods Seventy-eight patients with PCI admitted to Neurological Intensive Care Unit( NICU)were collected. The relationship between their 90 days outcome evaluated the modified Rankin score( mRS) were respectively analyzed with their baseline scores of Glasgow Coma Scale( GCS) and posterior circulation-ASPECTS( pc-ASPECTS) as well as the presence of early neurological deterioration. Results Compared with those of pcASPECTS scores ≥ 8,patients with pc-ASPECTS scores < 8 had higher baseline NIHSS scores,lower baseline GCS scores and poor outcomes. Baseline GCS scores( P = 0. 018),pc-ASPECTS scores( P = 0. 001) and the presence of early neurological deterioration( P = 0. 001) were related with the 90 days scores of mRS. Conclusion In the early stage of the PCI,patient baseline GCS score ≤8,pc-ASPECTS score < 8 and the presence of early neurological deterioration predict unfavorable outcome.更多还原