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乳腺癌应用保乳术辅助放疗的临床疗效观察

The Observation on the Clinical Curative Effect of Breast Conserving Surgery with Adjuvant Radiotherapy in Breast Cancer

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【作者】 翟静张鹏程耿凯曹永珍

【Author】 ZHAI Jing;ZHANG Peng cheng;GENG Kai;CAO Yong zhen;Department of Radiation Oncology,General Hospital of Tianjin Medical University;

【机构】 天津医科大学总医院肿瘤放射治疗科

【摘要】 目的探究乳腺癌应用保乳术辅助放疗治疗的临床疗效观察。方法资料随机选自2011年6月-2013年6月在本院诊治的乳腺癌患者62例,按照随机随机数字表方法将患者分为两组,每组31例,以保乳术辅助放疗患者作研究组,以改良式根治手术辅助化疗治疗作对照组,分析两组患者治疗后的美容效果、相关治疗指标、皮肤分级以及预后情况。结果研究组乳房的美容效果优良率77.42%,对照组32.26%,两者比较具统计学意义(P<0.05);且两组就出血量、手术时间情况,比较具有统计学意义(P<0.05);同时两组放疗后皮肤反应各分级的例数,以及患者预后的局部复发率、远处的转移率、生存率情况比较,差异不具有统计学意义(P>0.05)。结论对于乳腺癌患者应用保乳术辅助放疗治疗,效果显著,具有一定临床研究和应用价值。

【Abstract】 Objective To observe the clinical effect of breast conserving surgery with adjuvant radiotherapy in breast cancer. Methods 62 cases of patients with breast cancer in our hospital from 2011 June-2013 June were selected randomly,and were divided into two groups,31 patients per group,breast conserving surgery with adjuvant radiotherapy in patients as study group,modified radical surgery with adjuvant chemotherapy as control group,analysis two group patients after treatment,cosmetic effect,therapeutic index,skin classification,and prognosis. Results The study group breast cosmetic results excellent rate of 77. 42%,higher than 32. 26% in the control group,significant differences with statistical significance( P < 0. 05);and the research group of bleeding volume,operation time,less than the control group,significant differences with statistical significance( P < 0. 05); at the same time case the number of each grade of two groups of skin reactions after radiotherapy,and the prognosis of patients with local recurrence rate,distant metastasis rate,survival rate is the difference was not statistically significant( P > 0. 05). Conclusion Application of breast conserving surgery with adjuvant radiotherapy for breast cancer patients,significant effect,has a certain clinical value in research and application.

【关键词】 乳腺癌保乳术放疗疗效
【Key words】 Breast CancerBreast Conserving SurgeryRadiotherapyClinical Effect
  • 【文献出处】 中国辐射卫生 ,Chinese Journal of Radiological Health , 编辑部邮箱 ,2014年03期
  • 【分类号】R737.9
  • 【被引频次】4
  • 【下载频次】54
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