【摘要】 目的探讨血清孕酮水平对判断妊娠结局的指导价值。方法门诊收集停经60 d内、血人绒毛膜促性腺激素(HCG)阳性且初诊时测定血孕酮值的孕妇140例,随访盆腔B超和孕酮值直至确诊。根据妊娠结局分为宫内早孕组、先兆流产组、稽留流产组、异位妊娠组,对各组孕妇的孕酮值进行统计分析。结果孕酮值宫内早孕组>先兆流产>难免流产>异位妊娠组,且差异有统计学意义(P<0.05)。宫内早孕组与稽留流产组间、宫内早孕组与异位妊娠组间孕酮值无论初诊或确诊差异均有统计学意义。先兆流产组与稽留流产组初诊时孕酮值差异无统计学意义,但确诊时差异有统计学意义;稽留流产组与异位妊娠组间初诊时孕酮值差异有统计学意义,但当稽留流产明确诊断时与异位妊娠组间孕酮值差异无统计学意义。结论定期监测血清孕酮,结合病史及B超、血HCG结果,能有效鉴别诊断宫内孕与异位妊娠,并对判断宫内早孕者胚胎能否正常发育具有重要的参考价值。更多还原

【Abstract】 Objective To investigate the serum progesterone levels in early pregnancy and pregnancy outcomes. Methods Serum progesterone levels at first visit of 140 pregnant women with menolipsis in 60 days and blood human chorionic gonadotropin(HCG) positive were collected in our clinic. The follow-up examination with B ultrasound detection and serum progesterone levels were measured until confirmation. In terms of pregnant results, 140 cases were divided into four groups which were early pregnancy in uterus, threatened abortion, missed abortion and ectopic pregnancy. And statistic analysis was executed for serum progesterone. Results By statistic analysis, serum progesterone values had significant differences among four groups. Serum progesterone levels of newly diagnosed or confirmed had significant difference between the intrauterine pregnancy group and missed abortion group, between intrauterine pregnancy group and ectopic pregnancy group. Serum progesterone levels had no significant difference between threatened abortion and missed abortion at first visit, but with significant difference at confirmation. Serum progesterone levels had significant difference between missed abortion and ectopic pregnant at first visit,but with no significant difference at confirmation. Conclusion By monitoring serum progesterone and combined with medical history, type-B ultrasonic inspection and blood HCG results, we could effectively identify intrauterine pregnancy and ectopic pregnancy, and promptly judge the later development of embryo.更多还原