【摘要】 流行病学研究表明,微生物和微生物组分对过敏性疾病及慢性炎性疾病有保护作用。在生命早期使用益生元、益生菌,可以通过早期的肠道菌群定植形成稳定内环境和免疫耐受,以及一级预防减少过敏性疾病及慢性炎性疾病的发生;应用细菌溶解物可以预防哮喘和感染性疾病,减少反复感染的几率。本文对益生元、益生菌和细菌溶解物对婴幼儿免疫功能的作用进行综述,探讨目前研究存在的问题,并对未来的临床研究提出改进设想和方向。更多还原

【Abstract】 Epidemiological studies have shown that microorganisms and microbial components have protective effect against allergic diseases and chronic inflammatory diseases. Most results show that using prebiotics,probiotics in early life can develop a stable internal environment and immune tolerance with gut microbiological colonization,and reduce the incidence of allergic and inflammatory diseases by primary prevention as well; while using bacterial lysates in early life can prevent the occurrence of asthma and infectious diseases,and reduce the chances of recurrent infection. This article aims to review the effects of probiotics,prebiotics and bacterial lysate on infants’ immunity,and discuss the existing problems in current,so as to put forward improving suggestions and directions for future clinical research.更多还原