【摘要】 目的:探讨冠心病介入治疗后cTn-T的变化,分析cTn-T升高的相关因素及对病人临床预后的影响。方法:选择在我院成功行PCI手术的60例冠心病病人,测定PCI前、后24 hcTn-T水平,并详细记录临床资料及PCI术中的相关操作因素,按照术后cTn-T升高与否,分为升高组(21例)和正常组(39例)。比较两组间冠脉病变支数及手术相关操作因素的差别。并进行院内随访,观察病人临床结局。结果:冠心病病人介入治疗后cTn-T升高率为35%,cTn-T升高组和cTn-T正常组在年龄、性别、体重指数、吸烟史、高血压史、糖尿病史、高血脂、病变血管支数方面的差别无统计学意义(P值>0.05)。在支架释放及血管扩张时压力总合、球囊扩张时间总和、球囊扩张次数、支架长度、支架直径及支架数目方面的差别有统计学意义(P值<0.05)。cTn-T升高组较cTn-T正常组,心纹痛症状发生者较多,且cTn-T升高组病人住院时间明显延长。结论:PCI术可引起心肌损伤,且与支架释放及血管扩张压力总合、球囊扩张时间总和、球囊扩张次数、支架数目、支架长度、支架直径有关。并能在一定程度上决定病人的预后。更多还原

【Abstract】 Objective:To observe the change of cardiac troponin-T( cTn-T) after percutaneous coronary intervention( PCI). The factors with related to intervention procedures to patients with cTn-T elevation after PCI and the impact of the risk of cTn-T on the clinical outcomes were investigated. Methods:60 patients were chosen after successful PCI in our hospital. cTn-T levels were measured before and at 24 h after the procedure,the clinical characteristics of patients and factors with related to intervention procedures were recorded. The patients with normal cTn-T before PCI were classified into groupⅠ( cTn-T positive,21 cases) and group Ⅱ( cTn-T negative,39 cases) by levels of cTn-T post intervention. Comparison about the number of lesion vessels and the relative factors in PCI were performed between two groups. The clinical outcomes of the patients were follow-up. Results:The positive rate of cTn-T was 35% after PCI. The differences in sex、age、BMI、history of smoking,、hypertension,、diabetes mellitus、hyperlipidemia and the number of lesion vessels were no statistical significance between every two groups( P > 0. 05). There were statistical differences in inflation pressure、total time of inflation、dilated times、length and diameter of stent and the number of stents between groupⅠand group Ⅱ( P < 0. 05). The angina onsets were more common and the length of stay were longer in the patients with the rise of cTn-T than those without. Conclusion:PCI may cause myocardial injury,which is associated to inflation pressure、total time of inflation、dilated times,length and diameter of stent and the number of stents. To a certain extent the level of troponin Can predict the outcomes.更多还原