【摘要】 目的:探讨骨髓穿刺和骨髓活检在结直肠癌贫血中的诊断价值。方法:对257例结直肠癌患者行骨髓穿刺和骨髓活检,检测癌细胞浸润,分析其贫血状况。结果:结直肠癌贫血发生率为47.86%(123/257例)。右半结肠癌和直肠癌以缺铁性贫血为主(P<0.05)。左半结肠癌以多因素贫血和巨幼细胞性贫血为主,差异有统计学意义(P<0.05)。结直肠癌伴贫血患者中肿瘤骨髓侵润占8.13%,以低/未分化患者肿瘤骨髓侵润发生率较高(P<0.05),骨髓穿刺与骨髓活检诊断符合率为70%,所有骨髓侵润患者均有不同程度的骨髓纤维组织增生。结论:骨髓穿刺和骨髓活检在结肠癌贫血的诊断中有重要临床意义。更多还原

【Abstract】 Objective: To explore the value of bone marrow puncture and biopsy in diagnosis of anemia in colorectal cancer. Methods: Bone marrow puncture and biopsy were conducted in 257 cases with colorectal cancer for further understanding the bone marrow metastasis and analyzing the state of anemia. Results: Incidence of anemia in patients with colorectal cancer was 47. 86%( 123 /257). Right colon cancer and rectal cancer were mostly with iron deficiency anemia( P < 0. 05),while left colon cancer mostly due to multiple factors and megaloblastic anemia( P < 0. 05). There was 8. 13% of patients with bone marrow infiltration in colorectal cancer patients,especially in low differentiation and undifferentiation cases( P < 0. 05). Diagnostic accordance rate achieved by bone marrow puncture and diagnose was 70%. Various degree of proliferation of bone marrow fibrous tissue occurred in all patients. Conclusion: Bone marrow puncture and biopsy play important roles in diagnosing anemia in colorectal cancer.更多还原