【摘要】 目的:比较苄星青霉素治疗合并HIV感染的梅毒和非合并HIV感染梅毒的疗效。方法:对来自VCT门诊男男人群合并HIV感染的梅毒患者(A组31例)和非合并HIV感染的梅毒患者(B组64例)均给予苄星青霉素240万U肌肉注射,每周1次,共3次,分别于治疗后的第3、6、9、12个月门诊随诊,比较两组患者的临床及血清学疗效。结果:治疗后的第3、6、9、12个月A组总有效率分别为80.65%、83.87%、82.14%和85.19%,B组分别为81.25%、83.61%、86.89%和91.67%,两组差异均无统计学意义(P>0.05)。结论:苄星青霉素治疗男男性行为人群中HIV合并梅毒感染和单纯梅毒感染的疗效相当。更多还原

【Abstract】 Objective:To compare the therapeutic efficacy of benzathine penicillin in the treatment of patients with syphilis without complicated with HIV infection and those co-infected with HIV.Methods:Ninety-five patients with syphilis were recruited from MSM population(men who have sex with men) in VCT clinics and treated with benzathine penicillin 2.4 million units,weekly for 3 weeks.Thirty-one patients were co-infected with HIV(group A) and 64 patients were not complicated with HIV infection(group B).Results;the total effective rate of RPR in the A group was 80.65%,83.87%,82.14%and 85.19%,while in B group was81.25%,83.61%,86.89%,91.67%at month 3,6,9 and 12 months respectively,Which showed no statistical significance(P>0.05).Conclusion;Benzathine penicillin is effective in treating both patients with syphilis without complicated with HIV infection and those who are co-infected with HIV.更多还原