【摘要】 目的观察氧气驱动(氧驱)雾化吸入治疗小儿支气管哮喘急性发作的临床效果。方法选取我院儿科门诊诊治的112例支气管哮喘急性发作的患儿,采用信封法随机分为2组,每组56例。对照组患儿采用支气管哮喘急性发作常规治疗,包括抗感染、止咳、化痰等对症支持治疗;观察组患儿在对照组基础上,采用氧驱雾化呼入布地奈德混悬液。治疗4 d后,仔细观察两组患儿咳嗽、呼吸困难等临床症状改善情况及肺部哮鸣音改善情况,并根据患儿各项症状、体征改善情况进行疗效评定。结果观察组患儿在氧驱雾化吸入治疗过程中,未见明显不良反应,均能顺利完成治疗。观察组、对照组的治疗总有效率分别为96.43%、85.71%,两组比较差异有统计学意义(P<0.05)。结论对于小儿支气管哮喘急性发作期患儿,采用常规综合治疗基础上加用氧驱雾化吸入布地奈德混悬液治疗,可取得满意的效果,而且患儿耐受性好。更多还原

【Abstract】 Objective To observe the effect of oxygen drive( oxygen flooding) inhalation treatment for children w ith acute exacerbation of bronchial asthma. Methods 112 children w ith acute exacerbation of bronchial asthma in hospital w ere randomly divided into tw o groups by envelope method,56 cases in each group. Patients in control group w ere treated w ith conventional treatment including anti-infective,cough,phlegm and other symptomatic and supportive treatment,patients in observation groups w ere given oxygen flooding atomization incoming budesonide on the basis of control group. After 4 d of treatment,the coughing,breathing difficulty and other clinical symptoms and w heezing lungs w ere observed,and the efficacy of the tw o groups w as evaluated closely according to the improvement of various symptoms and signs. Results No significant adverse reaction w as found in the patients of the tw o groups,all the children could complete the treatment successfully. The total effective rate of observation group and control group w ere96. 43% and 85. 71%,there w ere significant differences betw een the tw o groups( P < 0. 05). Conclusion Conventional therapy combined w ith oxygen flooding budesonide inhalation therapy has satisfactory effect on children w ith acute exacerbation of bronchial asthma and w ith good tolerance of children.更多还原