【摘要】 目的探讨冠状动脉钙化与急性心肌梗死之间的关系。方法 22 537例患者中,男13 204例,女9 333例,年龄(58.53±9.48)岁,共有急性心肌梗死患者2 254例。依据冠状动脉造影术中能否发现冠状动脉钙化分为钙化组(A组)和无钙化组(B组),统计两组间心肌梗死发病率的区别,并探讨其原因。结果钙化组心肌梗死患病率明显高于无钙化组,差异有统计意义(18.16%vs.8.84%,P<0.001);钙化组较无钙化组男性多见(62.46%vs.58.04%,P<0.001)、年龄偏大[(64.61±7.92)岁vs.(57.67±9.37)岁,P<0.001];糖尿病(25.64%vs.15.28%,P<0.001)、原发性高血压(高血压)发病率高(74.00%vs.57.13%,P<0.001);易发生血管病变(93.70%vs.7.32%,P<0.001),且以多支血管病变为主。即使在心肌梗死患者中,钙化组血管病变的发生率及多支血管病变所占比例也超过非钙化组,差异有统计意义(99.61%vs.94.32%,P<0.05;91.18%vs.66.23%,P<0.05)。两组均以ST段抬高型急性心肌梗死为主,两组心肌梗死部位比较,差异无统计学意义(P>0.05)。结论冠状动脉钙化患者,男性多见、年龄偏大;糖尿病、高血压发病率高;易发生血管病变,容易导致心肌梗死。更多还原

【Abstract】 Objectives To evaluate the relationship between coronary artery calcium and acute myocardial infarction.Methods Among the 22 537 patients [13 204 males, 9 333 females, age(58.53 ±9.48) years] recruited in this retrospective study,2 254 patients had acute myocardial infarction. According to their outcomes of percutaneous transluminal angiography, patients were divided into group A(with coronary artery calcium) and group B(without coronary artery calcium). The morbidity of acute myocardial infarction was calculated and compared between the two groups. Results Morbidity of acute myocardial infarction in group A was significantly higher than that in group B(18.16% vs. 8.84%, P<0.001). In contrast to group B, group A had more males(62.46% vs. 58.04%, P <0.001),older age [(64.61 ±7.92) years vs.(57.67 ±9.37) years, P <0.001], more diabetes cases(25.64% vs. 15.28%, P <0.001), more hypertensive cases(74.00% vs. 57.13%, P<0.001) and was more likely to have coronary artery disease(93.70% vs. 7.32%, P<0.001), especially multivessel disease. Even in patients with myocardial infarction, the rate of patients had blood vessel disease in group A was much more than that in group B(99.61% vs. 94.32%, P<0.05), and group A had more cases with multivessel disease(91.18% vs.66.23%,P <0.05). Patients were mainly with acute STsegment elevation myocardial infarction in both groups. Sites of myocardial infarction between the two groups were without statistical difference(P>0.05). Conclusions Patients who had coronary artery calcium are easily found in males,and of them,who with older age, diabetes, hypertension and coronary artery disease can easily lead to myocardial infarction.更多还原