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老年性脑微出血的磁共振成像研究
MRI of cerebral microbleeds in the elderly
【摘要】 目的探讨老年性脑微出血(CMB)的检出率及分布特征。方法回顾性分析2012年1月~2013年12月行头颅磁共振检查的老年受试者638例,按年龄分为60~69岁357例,70~79岁244例和≥80岁37例。采用常规MRI扫描和磁敏感加权成像序列,分别记录皮质及皮质下区、基底节、丘脑、小脑、脑干CMB的个数并进行分级。结果 638例中伴有CMB者195例,CMB检出率为30.6%,CMB的检出率随年龄增长而增加(χ2=10.963,P=0.000),CMB分级与年龄呈正相关(r=0.153,P<0.01);与60~69岁和70~79岁比较,≥80岁患者脑干CMB发生率明显升高,差异有统计学意义(23.58%vs 15.42%和12.78%,P<0.05)。结论 CMB发生率及分级与年龄呈正相关,磁共振成像对老年人群CMB的检出具有重要的临床意义。
【Abstract】 Objective To study the detection rate and distribution features of cerebral microbleeds(CMB)in the elderly.Methods CMB in 638 elderly subjects who underwent cerebral MRI in our hospital from January 2012 to December 2013 were retrospectively analyzed.The number of CMB in cortical area,subcortical area,basal ganglia area,thalamus,brain stem and cerebellum was recorded and graded by conventional MRI and susceptibility-weighted imaging.Results CMB were detected in 195 out of the 638 elderly subjects with a detection rate of 30.6%.The detection rate of CMB increased with the age(χ2=10.963,P=0.000)and the grade of CMB was positively associated with the age(r=0.153,P<0.01).The incidence of CMB was significantly higher in patients aged >80years than in those aged 60-69 years and 70-79years(23.58% vs 15.42%,23.58%vs 12.78%,P<0.05).Conclusion The incidence and grade of CMB are positively related with age.MRI plays an important role in detecting CMB in the elderly.
【Key words】 cerebral hemorrhage; magnetic resonance imaging; cerebrovascular disorders; hemosiderin;
- 【文献出处】 中华老年心脑血管病杂志 ,Chinese Journal of Geriatric Heart Brain and Vessel Diseases , 编辑部邮箱 ,2014年12期
- 【分类号】R743.34;R445.2
- 【被引频次】6
- 【下载频次】110