【摘要】 目的研究蒙特利尔认知评估量表(MoCA)在健康体检人群中的分布特征。方法选择1350例健康体检者,采用北京版MoCA对受试者进行认知功能测评。最终777例进入分析,按年龄分为:<65岁组175例,65~69岁组200例,70~74岁组145例,75~79岁组124例,≥80岁组133例;按受教育年限分为:≤12年组153例和13~20年组624例。结果不同年龄组、不同受教育年限组MoCA总分比较,差异有统计学意义(P<0.01)。多元线性回归方程显示,年龄与MoCA总分呈负相关(β=-0.639,P=0.000),受教育年限与MoCA总分呈正相关(β=0.741,P=0.000)。以均数-1.5倍标准差为轻度认知障碍筛查的参考值,筛查值范围分别为:<65岁组≤25分,65~69岁组≤24分,70~74岁组≤24分,75~79岁组≤23分,≥80岁组≤19分;≤12年组≤20分,13~20年组≤24分。结论在健康体检人群中,用MoCA进行认知功能障碍患者的筛查界值不同,尤其在低文化程度和高龄人群更需注意。更多还原

【Abstract】 Objective To study the application of MoCA Scale in cognitive function assessment of healthy subjects.Methods The cognitive function of 1350healthy subjects was assessed according to the MoCA Scale(Beijing version).Of the 857volunteers with their cognitive function assessed according to the the MoCA Scale(Beijing version),777were included in our analysis except for 80who were diagnosed with cognitive impairment.The 777subjects were divided into< 65years old group(n=175),65-69years old group(n=200),70-74years old group(n=145), 75-79years old group(n=124),and≥80years old group(n=133),and into≤12years education group(n=153)and 13-20years education group(n=624).Results The total MoCA score was significantly different in different age groups and different education years groups(P< 0.01).However,the time and place orientation score were significantly different in the other groups(P<0.05).However,the naming and digital width score were significantly different in the other groups(P<0.05).Multivariate linear analysis showed that age was negatively related with the total MoCA score(β=-0.639,P=0.000),education years were positively related with the total MoCA score(β=0.741,P=0.000).The MoCA score was≤25in<65years old group,≤ 24in 65-69years old group,≤24in 70-74years old group,≤23in 75-79years old group,≤ 19in≥80years group,and≤20in≤12years education group,≤24in 13-20years education group.Conclusion The MoCA score of cognitive imairment is different in healthy subjects,attention should thus be paid to different individuals,especially to those with a lower education level and those at advanced age.更多还原