【摘要】 目的:总结我院抗感染药物不良反应/事件(ADR/ADE)报告的相关因素,了解抗感染药物ADR/ADE发生特点及规律,以促进抗菌素的合理应用。方法:回顾性分析我院2008年1月至2013年12月收集的522例抗感染药物ADR/ADE报告。结果:522例抗菌药品ADR/ADE报告中,女性多于男性;1-14岁的儿童106例(20.31%),50-86岁的患者282例(54.03%);头孢菌素类239例(45.79%),喹诺酮类121例(23.18%)。抗菌药物ADR/ADE累及的系统-器官是皮肤及其附件129例(24.72%),消化系统108例(20.69%),呼吸系统97例(18.59%)。结论:加强对抗感染药物的护理,建立更好的抗生素不良反应的护理措施,可保证患者用药安全。更多还原

【Abstract】 Objective;To summarize the relevant factors of adverse drug reactions/events(ADR/ADE) reports of antibacterial agents in order to realize the characteristics and rules to improve rational use of antibiotics.Methods;The ADR/ADE reports of 522 antibacterial agents were collected and analyzed retrospectively from Jan 2006 to Dec2011 in our hospital.Results;Among the 522 cases of antibacterial agents ADR/ADE,females was slightly more than males,106(20.31%) cases were 0-14 years,282(54.03%) cases were 50 to 86 years,while it caused by cephalosporins and quinolones were 239 cases(45.79%)and 121 cases(23.18%).The vulnerable system/organ of antibacterial agents ADR/ADE were skin and its appendages(129 cases,24.72%),digestive system(108 cases,20.69%)and respiratory;system(97 cases,18.59%).Conclusions;It can ensure clinical safety of using antibiotics to strengthen antibacterial agents nursing and monitoring of antibacterial agents ADR/ADE.更多还原