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新型疏水性酶载体的合成及其性能研究

SYNTHESIS AND PROPERTIES OF NOVEL HYDROPHOBIC ENZYME CARRIERS

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【作者】 陈利唱润芳李晓蒙于浩峰马苓崔强金晓农路延龄

【Author】 CHEN Li;CHANG Runfang;LI Xiaomeng;YU Haofeng;MA Ling;CUI Qiang;JIN Xiaonong;LU Yanling;Tianjin Nankai Hecheng Science and Technology Co.Ltd.;

【机构】 天津南开和成科技有限公司

【摘要】 研究了聚丙烯酸酯类疏水性固定化酶载体(包括环氧基和胺基)的合成,旨在提高载体固载酶的性能。结果表明,所得载体的孔结构适合固定化青霉素酰化酶、D-氨基酸氧化酶、DL-7-ACA酰化酶、头孢菌素C酰化酶等。固定化D-氨基酸氧化酶的酶活与载体的含水量(与其孔结构相关)有密切的关系;载体的突出优点是固载酶时,酶的固定化效率可高达50%。

【Abstract】 This paper studied the synthesis of hydrophobic polyacrylate enzyme carriers, aimed at improving its immobilization performance. The results showed that the pore structure was suitable for immobilizing penicillin acylase, D-amino acid oxidase, and DL-7-ACA acylase. And the enzyme activity of D-amino acid oxidase immobilized had a close relationship with the water content of the carriers(mainly depending on the pore structure); the major advantage of these carriers was that the immobilized efficiency was up to 50% during the enzyme immobilization.

  • 【文献出处】 离子交换与吸附 ,Ion Exchange and Adsorption , 编辑部邮箱 ,2014年02期
  • 【分类号】TQ464.8
  • 【下载频次】107
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