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胸水同型半胱氨酸癌胚抗原724β2微球蛋白联合检测的临床价值
Clinical value of hydrothorax homocysteine,carcinoembryonic antigen 724 and β2 microglobulin combined detection
【摘要】 目的 探讨胸水同型半胱氨酸、癌胚抗原724、β2微球蛋白联合检测的临床价值。方法对44例恶性胸水患者及43例良性胸水患者的胸水进行同型半胱氨酸、癌胚抗原724、β2微球蛋白联合检测分析。结果 恶性胸水患者胸水同型半胱氨酸、癌胚抗原724、β2微球蛋白水平均显著高于良性胸水患者(P<0.01);恶性胸水患者胸水同型半胱氨酸、癌胚抗原724、β2微球蛋白单项检测阳性率分别为75.0%、84.09%、81.82%,3项联合检测阳性率(86.36%)高于单项检测结果。结论 胸水同型半胱氨酸、癌胚抗原724、β2微球蛋白联合检测对鉴别恶性与良性胸水有较高的临床价值。
【Abstract】 Objective To investigate the clinical value of hydrothorax homocysteine,carcinoembryonic antigen 724(CEA 724) and β2 microglobulin combined detection.Methods Combined detections and analyses of hydrothorax homocysteine,CEA 724 and β2 microglobulin were conducted in 44 patients with malignant hydrothorax and 43 ones with benign hydrothorax.Results Hydrothorax homocysteine,CEA 724and β2 microglobulin levels were significantly higher in patients with malignant hydrothorax than ones with benign(P<0.01);single-item detection positive rate of homocysteine,CEA 724 and β2 microglobulin were 75.0%,84.09%and 81.83%respectively in patients with malignant hydrothorax,3-item combined detection positive rate(83.36%) was higher than single-item.Conclusion Hydrothorax homocysteine,CEA 724 and β2 microglobulin combined detection has higher clinical value for differentiating malignant from benign hydrothorax.
【Key words】 Hydrothorax; homocysteine; CEA 724; β2 microglobulin; combined detection; malignancy; benign; tumor marker; differential diagnosis;
- 【文献出处】 临床心身疾病杂志 ,Journal of Clinical Psychosomatic Diseases , 编辑部邮箱 ,2014年03期
- 【分类号】R730.4