【摘要】 目的探讨急性脑干梗死患者预后不良的预测因子。方法收集并记录133例急性脑干梗死患者的临床资料。根据患者发病30 d时改良的Rankin量表(mRS)评分及是否死亡判断预后。采用多因素Logistic回归分析法分析急性脑干梗死患者预后不良的预测因子。结果本组患者发病30 d时预后不良31例(23.3%),其中死亡5例,严重残障26例。与预后良好患者比较,预后不良患者入院时有意识障碍和脑部多发梗死灶的比例以及美国国立卫生研究院卒中量表(NIHSS)评分明显增高(均P<0.05)。多因素Logistic回归分析显示:脑部多发梗死灶(OR=6.819,95%CI:1.615~28.797,P<0.01)和入院时NIHSS评分(OR=1.242,95%CI:1.068~1.443,P<0.01)是急性脑干梗死患者预后不良的独立预测因子。结论脑部多发梗死灶和入院时NIHSS评分是急性脑干梗死患者预后不良的独立预测因子。更多还原

【Abstract】 Objective To investigate the predictors of poor prognosis in patients with acute brainstem infarctions. Methods The clinical information of 133 patients with acute brainstem infarction was collected and recorded. The prognosis was evaluated by modified Rankin scale( mRS) score and whether the patient was dead or not at 30 d after onset. A multiple logistic regression was performed to analyze the predictors of poor prognosis in patients with acute brainstem infarction. Results There were 31 cases( 23. 3%) had poor prognosis at 30 d after onset,including 5 dead cases and 26 cases with severe disable. Compared with patients with good prognosis,the rates of disturbance of consciousness,multiple infarcts and the scores of national institutes of health stroke scale( NIHSS) in patients with poor prognosis were significantly higher( all P < 0. 05). Multiple logistic regression analysis showed that multiple infarcts( OR = 6. 819,95% CI: 1. 615- 28. 797,P < 0. 01) and NIHSS scores at admission( OR = 1. 242,95% CI: 1. 068- 1. 443,P < 0. 01) were independent predictors of poor prognosis in patients with acute brainstem infarction. Conclusion Multiple infarcts and NIHSS scores at admission were independent predictors of poor prognosis in patients with acute brainstem infarction.更多还原