【摘要】 目的探讨短暂性脑缺血发作(TIA)样缺血性卒中患者颅内外动脉狭窄的年龄分布特征。方法回顾性分析173例TIA样缺血性卒中患者的全脑血管DSA资料,对其中有颅内和/或颅外血管狭窄表现的162例患者按年龄分为<50岁(61例)和≥50岁(101例)两组。计算和比较两组患者颅内、外动脉狭窄及闭塞的发生率,并行统计学检验。结果单纯颅内动脉狭窄及闭塞发生率:<50岁组为54.1%(33/61),≥50岁组为20.8%(21/101)(χ2=18.985,P<0.05);单纯颅外动脉狭窄及闭塞发生率:<50岁组为14.8%(9/61),≥50岁组为28.7%(29/101)(χ2=4.127,P<0.05);颅内、外动脉同时狭窄及闭塞发生率:<50岁组为31.1%(19/61),≥50岁组为50.5%(51/101)(χ2=5.801,P<0.05)。结论 TIA样缺血性卒中患者颅内、外动脉狭窄及闭塞的发生率有一定的年龄分布特征。单纯颅内动脉狭窄及闭塞多见于低龄患者,单纯颅外动脉和颅内、外动脉同时狭窄及闭塞多见于高龄患者。更多还原

【Abstract】 Objective To investigate the age distribution of intra-and extra-cranial artery stenosis in patients with TIAkind ischemic stroke.Methods A total of 173 patients with TIA-kind ischemic stroke were enrolled in this study.DSA materials were retrospectively analyzed.Among 173 patients,162 showed intra-cranial or extra-cranial artery stenosis.The162 patients were divided into < 50 years old group(n=61) and ≥50 years old group(n=101).The incidences of intra-cranial and extra-cranial artery stenosis or occlusion in the two groups were calculated,and the results were statistically compared between the two groups.Results The incidences of pure intra-cranial artery stenosis and occlusion was in < 50 years old group and ≥50 years old group were 54.1%(33 /61) and 20.8%(21 /101) respectively(χ2= 18.985,P < 0.05),while the incidences of pure extra-cranial artery stenosis and occlusion in < 50 years old group and ≥50 years old group were 14.8%(9 /61) and 28.7%(29 /101) respectively(χ2= 4.127,P < 0.05).The incidences of intracranial together with extra-cranial artery stenosis and occlusion in < 50 years old group and ≥50 years old group were 31.1%(19 /61) and 50.5%(51 /101) respectively(χ2= 5.801,P < 0.05).Conclusion In patients with TIA-kind ischemic stroke,the intra-cranial and extra-cranial artery stenosis and occlusion carry certain age-related distribution characteristics.Simple intra-cranial artery stenosis and occlusion are more commonly seen in young patients,while involvement of simple extra-cranial artery as well as both intra- and extra-cranial artery is often found in aged patients.更多还原