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血清降钙素原预测社区获得性肺炎病情严重程度的临床研究
Clinical study of serum procalcitonin to predict severity in elderly patients with community-acquired pneumonia
【摘要】 目的探讨血清降钙素原在评估社区获得性肺炎(CAP)病情严重程度的临床价值。方法收集2011年1月~2012年12月在西丽人民医院接受治疗的CAP患者80例,分≥65岁组50例;<65岁组30例,评价两组患者血清降钙素原、C-反应蛋白、白细胞计数、CURB-65和肺炎严重程度指数(PSI)之间的相关性。结果血清降钙素原(PCT)与CURB-65、PSI在总体上具有正相关性。血清降钙素原和CURB-65在≥65岁组CAP中尤其具有显著的正相关(r=0.408)。C-反应蛋白或白细胞水平与CAP严重程度之间的相关性较低。结论血清降钙素原比C-反应蛋白、白细胞计数更有助于临床预测CAP的严重程度,尤其是对于年龄大于65岁的老年患者。
【Abstract】 Objective To evaluate the clinical value of procalcitonin as a predictor of severity in patients with community-acquired pneumonia( CAP). Methods 80 patients with CAP were divided into two groups( ≥65years,n = 50; < 65 years,n = 30). Their procalcitonin,C-reactive protein( CRP),white blood cell,confusion,uremia,respiratory rate,blood pressure,CURB-65 and pneumonia severity of index( PSI) were recorded. Results The level of procalcitonin was positively correlated with CURB-65 and PSI,which was especially stronger in the elderly group( r = 0. 408). The correlation between the levels of CRP or WBC and CAP severity was low. Conclusion The level of procalcitonin is more useful than the levels of CRP or WBC to predict the severity of CAP.
【Key words】 community-acquired pneumonia; procalcitonin; C-reactive protein;
- 【文献出处】 临床肺科杂志 ,Journal of Clinical Pulmonary Medicine , 编辑部邮箱 ,2014年07期
- 【分类号】R563.1
- 【被引频次】14
- 【下载频次】73