【摘要】 目的探讨微生态制剂培菲康对老年肺炎患者抗生素相关性腹泻(AAD)的预防作用。方法选择76例老年肺炎患者随机分成试验组(n=38)和对照组(n=38)。两组患者均静脉应用>2种抗菌药物连续治疗>7 d,在抗感染治疗的同时,试验组加用微生态调节剂培菲康7 d。比较分析两组患者AAD的发生情况。结果试验组患者的AAD发生率为7.89%,对照组为31.58%,具有显著性差异(P<0.05);在抗菌治疗同时口服培菲康,试验组患者AAD发生率明显低于对照组。结论老年肺炎患者在应用抗菌药物治疗的同时,应用微生态制剂培菲康可有效预防AAD的发生。更多还原

【Abstract】 Objective To study the preventive effect of microecological modulators on antibiotic-associated diarrhea( AAD) in elderly patients with pneumonia. Methods 76 elderly patients with pneumonia were randomly divided into the treatment group( n = 38) and the control group( n = 38). All patients received combined antibiotics treatment for more than 7 days. The treatment group was additionally treated with microecological modulators for 7days. The incidence of AAD was compared between the two groups. Results The incidence of AAD was 7. 89% in the treatment group,and 31. 58% in the control group( P < 0. 05). Conclusion Microecological modulators can effectively prevent the occurrence of antibiotic-associated diarrhea.更多还原