【摘要】 采用粉末冶金法制备nHA-Mg复合材料,通过浸涂提拉法在nHA-Mg复合材料表面制备PLGA、nHA-PLGA涂层,利用SEM观察nHA-Mg-PLGA生物复合材料在模拟体液浸泡腐蚀后表面形态的变化,研究腐蚀时间与腐蚀液pH之间的关系。结果表明,PLGA涂层、nHA-PLGA涂层的加入减缓了材料的腐蚀速率,降低了材料降解时的pH值;nHA加入到涂层中,减缓了材料的腐蚀速度,提高了复合材料的生物相容性。结论:nHA-Mg-PLGA生物复合材料减缓了镁合金的腐蚀速率,具有良好的抗腐蚀性能以及良好的生物相容性。更多还原

【Abstract】 Objective:To study the structure and corrosion resistance of nHA-Mg-PLGA biocomposites.Methods:In this paper we prepared nHA/Mg composite with powder metallurgy method.By dipcoating method we prepared PLGA and nHA/PLGA coatings on the surface of nHA/Mg composite material.Using the SEM we observted the changes of surface morphology of nHA/Mg/PLGA biocomposite materials in simulated body fluidim,and studied the relationship between the etching time and the etching solution pH.Results:The results showed that PLGA coatings and nHA/PLGA coatings which were added in to the Mg alloy slow down the corrosion rate,reduce the pH value of the time material degradation.Adding nHA into the PLGA coatings could play a role on the corrosion resistance of the coating.Conclusion:nHA/Mg/PLGA biocomposite material slows down the rate of corrosion,and has good corrosion resistance as well as good biocompatibility.更多还原