Objective To analyze and explore the causes of bone cement leakage in percutaneous vertebroplasty(PVP). Methods Clinical data about 105(146 vertebrae) patients who were treated by percutaneous vertebroplasty in our department from March 2011 to February 2014 were retrospectively analyzed. Postoperative X-ray and CT examination were performed in order to observe the bone cement leakage and analyze the related causes. Results The bone cement leaked in 47(63 vertebrae) patients with 4 cases in vertebral canal,...