In order to prepare a new sustained and controlled release drug carrier,the chitosan nanoparticles were prepared by inverse miniemulsion cross-linking technique with vacuum dehydration treatment.The mixture solution of paraffin and hexane was used as oil phase with chitosan solution as aqueous phase,Span- 80 as emulsifier and glutaraldehyde as cross-linking agent. The characteristics of the chitosan nanoparticles were determined by particle diameter distribution,SEM,FT- IR,TG and DSC. The results show that ...
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