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孕期营养补充剂抗疲劳、耐寒、耐热动物实验观察

Effect of pregnancy nutrition supplement on resistance of fatigue,cold and high temperature in mice

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【作者】 暴国王宁张树成王尚明王丽丽张斌张长勇石翠格徐祥波贺斌刘庆王介东

【Author】 Bao Guo;Wang Ning;Zhang Shucheng;Wang Shangming;Zhang Bin;Zhang Changyong;Shi Cuige;Xu Xiangbo;He Bin;Liu Qing;Wang Jiedong;National Research Institute for Family Planning;

【机构】 国家人口计生委科学技术研究所

【摘要】 目的:通过抗疲劳、耐寒、耐热实验分析孕期营养补充剂对小鼠机体生命活力的影响。方法:SPF级昆明小鼠随机分为高、中、低剂量和对照共4组,灌胃给药21d后,进行动物实验。结果:负重游泳时间在雌性小鼠的3个剂量组均明显增加(P均<0.05),在雄性小鼠的中、高剂量组明显增加(P<0.05);耐寒时间在雌性小鼠的中、高剂量组明显增加(P<0.01),在雄性小鼠的3个剂量组均明显增加(P<均0.05);耐热时间在雌性和雄性小鼠的中、高剂量组均明显增加(P<0.05)。结论:服用多种维生素、多种矿物质的营养补充剂的小鼠机体活力明显增加,抗疲劳、抗寒和抗热的能力显著提高。

【Abstract】 Objective:To explore the effect of pregnancy nutrition supplement on the resistance of fatigue,cold and high temperature in mice.Methods:SPF Kunming mice were randomly divided into 4groups.Twenty-one days after oral administration,the resistance of fatigue,cold and high temperature were evaluated.Results:The swimming time of female mice were significantly increased in 3does groups(Pall<0.05),and that was significantly increased in the medium-and high-does groups of male mice(P<0.05).The survival time of low temperature of female mice were significantly increased in medium- and high-does groups(P<0.01),and that was significantly increased in all 3 does groups of male mice(Pall<0.05).The survival time of high temperature of both male and female mice were significantly increased in the medium-and high-does groups(P<0.05).Conclusion:Pregnancy nutrition supplement could improve the resistance of fatigue,cold and high temperature in mice.

【基金】 国家科技基础性工作专项(2013FY110100);十二五国家科技支撑计划(2012BAI32B02);国家人口计生委科学技术研究所横向课题(2013HX001)
  • 【文献出处】 中国计划生育学杂志 ,Chinese Journal of Family Planning , 编辑部邮箱 ,2014年04期
  • 【分类号】R151.2
  • 【被引频次】3
  • 【下载频次】141
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