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早期胃癌的临床病理特点分析及随访观察结果

Analysis of the Clinicopathological Characteristics of Early Gastric Cancer and the Result of Follow-up Observation

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【作者】 李云辉林华欢孙艺李毅光

【Author】 LI Yunhui;LIN Huahuan;SUN Yi;LI Yiguang;Department of Pathology, Guangdong Jiangmen Xinhui People’s Hospital;Department of Pathology, Guangdong General Hospital;

【机构】 广东省江门市新会市人民医院病理科广东省人民医院病理科

【摘要】 目的分析早期胃癌的临床病理特点,观察患者术后生存情况。方法选择2010年10月—2012年3月来该院治疗早期胃癌的患者50例,对50例患者的临床病理特点及随访情况进行回顾。结果通过分析发现,高分化腺癌在贲门部的发生率明显高于胃体和胃窦部(P<0.05),低分化腺癌在胃窦部的发生率高于胃体和贲门部,但差异无统计学意义(P>0.05)。在检查癌灶<3 cm的早期胃癌患者中,发现粘膜内癌发生率明显于高于粘膜下癌的发生率(P<0.05)。而对于癌灶>3 cm的早期胃癌患者,粘膜下癌的发生率明显高于粘膜内癌的发生率(P<0.05)。经过早期手术治疗,患者的存活率明显增大。结论早期胃癌根据其分化不同生长的部位也不同,癌灶大小对癌组织的生长部位也有影响,所以临床医生在诊断,需要加强重视,避免漏诊,尽早检查胃癌,尽早治疗,能提高患者的生存时间。

【Abstract】 Objective To analyze the clinicopathological characteristics of early gastric cancer and observe the postoperative survival of the patients. Methods 50 cases with early gastric cancer treated in our hospital from October 2010 to March 2012 were selected, and the clinicopathological characteristics and result of follow-up of the patients were reviewed. Results It was found by the analysis that the incidence of well differentiated adenocarcinoma in cardia area was significantly higher than that in body of stomach and gastric antrum(P<0.05); the incidence of poorly differentiated adenocarcinoma in gastric antrum was higher than that in body of stomach and cardia area but with no significant difference(P>0.05). It was found that the incidence of intra-mucosal carcinoma was significantly higher than that of submucosal carcinoma in the examination of early gastric cancer patients with cancerous foci less than 3cm(P<0.05), while for the patients with cancerous foci greater than 3cm, the incidence of submucosal carcinoma was obviously higher than that of intra-mucosal carcinoma(P<0.05). After early operation treatment, the survival rate of the patients increased obviously. Conclusion The site of early gastric cancer is diverse due to different differentiation, and the size of the cancerous foci can affect the cancer tissue production site, therefore clinicians should strengthen the attention to diagnosis in order to avoid missed diagnosis, and detect and treat gastric cancer as soon as possible, thereby prolonging the survival time of the patients.

  • 【文献出处】 中外医疗 ,China & Foreign Medical Treatment , 编辑部邮箱 ,2014年26期
  • 【分类号】R735.2
  • 【被引频次】3
  • 【下载频次】62
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