【摘要】 目的观察安络化纤丸联合复方二氯醋酸二异丙胺治疗非酒精性脂肪肝的临床疗效及安全性。方法将66例非酒精性脂肪肝患者随机分为两组,治疗组36例,给予安络化纤丸联合复方二氯醋酸二异丙胺治疗,对照组30例,仅给予复方二氯醋酸二异丙胺治疗,疗程12周。结果治疗组的总有效率为91.67%,对照组的总有效率为80.0%,两组比较差异具有显著性(P<0.05)。治疗组治疗后的丙氨酸氨基转移酶(ALT)、谷氨酸氨基转移酶(AST)、γ-谷氨酰胺转肽酶(GGT)、甘油三酯(TG)、总胆固醇(TCH)等血清生化指标与治疗前相比较,差异均有显著性(P<0.05)。两组治疗后B超检测情况均较治疗前明显改善(P<0.05),与对照组比较,治疗组改善的更明显(P<0.05)。结论安络化纤丸联合复方二氯醋酸二异丙胺可安全有效地治疗非酒精性脂肪性肝病。更多还原

【Abstract】 Objective To observe the clinical therapeutic effect of Anluohuaxian pill combined with diisopropylamine ascorbate in treatment of non-alcoholic fatty liver. Methods 66 cases of non-alcoholic fatty liver were randomly divided into two groups. 36 cases of treatment group were treated with Anluohuaxian pill plus diisopropylamine ascorbate,30 cases of control group were treated with diisopropylamine ascorbate,both treated 12 weeks. Results The total effective rate in treatment group( 91. 67%) was significantly higher than in control group( 80. 0%)( P < 0. 05). The ALT,AST,GGT,TG and TCH levels of treatment group had significant improvement compared with before treatment( P < 0. 05). The ultrasonic inspection in both groups had significant improvement compared with before treatment( P < 0. 05),with the treatment group showing a better improvement than in control group,there were significant differences between the two groups( P < 0.05). Conclusion Anluohuaxian pill plus diisopropylamine ascorbate in treatment of non-alcoholic fatty liver was proved to be a safe and effective therapy and worthy of clinical application.更多还原