【摘要】 目的评价低分子肝素钙联合辛伐他汀治疗急性和进展性脑梗死的临床疗效。方法对2010年1月—2012年12月入住本院的85例急性脑梗死和37例进展性脑梗死,随意分成对照组和观察组,对照组:61例,其中急性脑梗死42例,进展性脑梗死19例,应用常规药物治疗;观察组:61例,其中急性脑梗死43例,进展性脑梗死18例,在常规药物治疗的基础上应用低分子肝素钙5000U/次,皮下注射,q12h,联合辛伐他汀滴丸20mg,每晚服用一次,疗程均为14d。治疗前后评定神经功能缺损程度、日常生活活动能力和运动功能确定有效率;评定血液流变学及血脂指标对比治疗效果。结果神经功能缺损程度减分显著、日常生活活动能力和运动功能评分较治疗前均有显著提高,对照组、治疗组有效率分别为86.88%和68.85%;血液流变及血脂指标显著改变。结论低分子肝素钙和辛伐他汀联合应用,在急性和进展性脑梗死的治疗中有确切的疗效。更多还原

【Abstract】 Objective To evaluate the clinical curative effect of Edaravone injection combined with Simvastatin pills in the treatment of Acute and Progressive Cerebral Infarction. Methods Totally 85 patients with Acute Cerebral Infarction and 37 patients with progressive cerebral infarction in our hospital from Dec 2010 to Dec 2012 were assigned to receive30 mg Edaravone injection wgtt q12 h combined with 20 mg Simvastatin pills abends einmal for 14 days,neurological function deficiency scale,hemodynamic indexes,activities of daily living and motor function were evaluated on pretherapy and post- treatment. Results Neurological function deficiency scale,hemodynamic indexes,activities of daily living and motor function had significant difference compared with pretherapy( P < 0. 05 or 0. 01). Conclusion Edaravone injection combined with Simvastatin pills was effective in the treatment of acute and progressive cerebral infarction.更多还原