【摘要】 目的探讨支气管哮喘与肺部感染的临床关系,指导临床早期诊断和治疗支气管哮喘合并肺部感染。方法回顾分析2012年6月至2013年6月在郑州大学第一附属医院呼吸内科就诊的70例支气管哮喘患者合并肺部感染的临床资料,包括一般资料、临床症状和体征及治疗效果。选出70例单纯支气管哮喘患者作为对照。采用SPSS 17.0统计软件对两组病例的临床资料进行统计学分析。结果 1支气管哮喘合并肺部感染,最常见的临床症状和体征:咳嗽、胸闷、胸痛、咳黄痰、桶状胸与单纯支气管哮喘组比较差异有统计学意义(P<0.05),而呼吸困难、哮鸣音与单纯支气管哮喘组比较差异无统计学意义(P>0.05)。2感染肺炎克雷伯菌(31/70,44.29%)、铜绿假单胞菌(10/70,14.28%)、绿脓杆菌(9/70,12.86%)、大肠埃希菌(10/70,14.28%)、葡萄球菌(4/70,5.71%)、白色念珠菌(6/70,8.57%)。两组治疗效果比较差异有统计学意义(P<0.05)。结论支气管哮喘合并肺部感染以肺炎克雷伯菌为主,对于支气管哮喘患者合并咳嗽、咳黄痰、胸闷、胸痛、桶状胸等应警惕合并肺部感染可能,应早期诊断与治疗。更多还原

【Abstract】 Objective To investigate the clinical correlation of patients with bronchial asthma combined with lung infection,in order to provide guidance on early diagnosis and treatment of them. Methods Retrospective analysis of clinical data of 70 patients of bronchial asthma combined with pulmonary infection and treated in the first affiliated Hospital of Zhengzhou university between June 2012 and June 2013,including the general information,clinical signs and symptoms and treatment effects. The control group included 70 patients with only bronchial asthma. The clinical data were analyzed using the SPSS 17. 0. Results 1The most common clinical symptoms and signs in the study group included cough,chest tightness,chest pain,cough yellow sputum,barrel chest,which showed significant differences from the control group( P < 0. 05). There were no statistically significant differences in difficulty in breathing and wheezing sounds between the study and control groups( P > 0. 05). 2 The rate of Klebsiella pneumonia was 44. 29% in the bacteria of pulmonary infection,the rate of Verdigris false single spore fungus was 14. 28% in the bacteria of pulmonary infection,the rate of Pseudomonas aeruginosa was 12. 86% in the bacteria of pulmonary infection,the rate of Escherichia coli was14. 28% in the bacteria of pulmonary infection,the rate of Staphylococcus aureus was 5. 71% in the bacteria of pulmonary infection,the rate of Candida albicans was 8. 57% in the bacteria of pulmonary infection. There were statistically significant differences in treatment effects between the study and control groups( P < 0. 05). Conclusion Bronchial asthma combined with pulmonary infection is given priority to Klebsiella pneumonia bronchial asthma with cough,cough yellow sputum,chest tightness,chest pain,barrel chest may be predisposed to have lung infection,should be given early diagnosis and treatment.更多还原