【摘要】 以对异丙基苯甲酸为原料经酯化、还原、氧化反应合成了对异丙基苯甲醛。其中催化剂DMF加快了酯化反应速率,质子缓释剂乙醇的加入使得还原产率提高了34.5%,当以浓硫酸为质子缓释剂时,对异丙基苯甲酸可被直接还原为醇,氧化剂KMnO₄-CuSO₄·5H₂O以KMnO₄含量为50%最佳。合成方法相对安全环保,产品纯度达到了98.6%,总产率达到了73.8%（以对异丙基苯甲酸计）。目标化合物和中间产物通过¹H NMR表征。更多还原

【Abstract】 4-Isopropylbenzaldehyde was synthesized by using 4-isopropylbenzoic acid as the starting material through estenfication,reduction and oxidation.In this paper,the rate of estenfication was accelerated by adding DMF.the yield of reduction was increased by 34.5%via adding ethanol and 4-isopropylbenzoic acid could be directly reduced to the alcohol by using concentrated sulfuric acid as the proton release agent,the best content of KMnO₄ in oxidant was 50%.Synthetic route was safe and environmental.The purity of object product was 98.6%,and the total yield reached 73.8%（calculated based on 4-isopropylbenzoic acid）.All structures were characterized by ¹H NMR.更多还原