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泽泻毒性现代研究进展

Modern research progress of toxicity of Alismatis Rhizoma

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【作者】 范稹

【Author】 FAN Zhen;Department of Blood Internal,First People’s Hospital of Jingmen;

【机构】 湖北省荆门市第一人民医院血液内科

【摘要】 泽泻为常用中药,一般认为其无毒。但部分书籍载其有毒,临床也有其致肝毒性的报道。目前对泽泻的水提物、醇提物等的毒性研究结果不一致,有的表明其总属无毒,有的表明其有一定肝毒性和肾毒性。而对其毒性成分的研究表明可能与其中的泽泻醇C、16,23-环氧泽泻醇B和泽泻醇O等有关。整体看来,目前对于泽泻可能毒性的相关研究较少。

【Abstract】 Alisma is commonly used in traditional Chinese medicine,and it is generally believed non-toxic. However,it is recorded toxic in some books,and there were also some hepatotoxicity report about it. Current toxicity research result of water extract and alcohol extract of Alismatis Rhizoma tis showed different results.,Some showed they are non-toxic,while some others showed certain hepatotoxicity and nephrotoxicity. Toxic ingredient research showed that the toxic components might be its alisma alcohol C, 16,23- epoxy alisma alcohol B and alisma alcohol O. From an overall point of view,researches on the toxicity of Alisma are few.

【关键词】 泽泻泽泻水提物肝毒性肾毒性
【Key words】 AlismaWater extract of AlismaHepatotoxicityNephrotoxicity
  • 【文献出处】 环球中医药 ,Global Traditional Chinese Medicine , 编辑部邮箱 ,2014年02期
  • 【分类号】R285.5
  • 【被引频次】12
  • 【下载频次】935
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