Objective To investigate the association between soluble P-selectin and cardiovascular autonomic neuropathy in patients with type 2diabetes mellitus(T2DM).Methods The plasma level of soluble P-selectin was measured in 42 normal subjects(control group),45 T2 DM patients(T2DM group)and 51 T2 DM patients complicated with cardiovascular autonomic neuropathy(DCAN group)by ELISA technique.Results The plasma levels of soluble P-selectin were(56.1±5.2),(33.5±7.8)and(18.7±6.3)μg/L in DCAN,T2 DM and control groups,sh...