【摘要】 目的探讨亚临床甲减对脑梗死患者颈动脉粥样硬化程度的影响。方法选取2011—2012年在我院诊治的26例单纯亚临床甲减患者(甲减组),25例单纯脑梗死患者(脑梗死组),22例亚临床甲减合并脑梗死患者(甲减合并脑梗死组),以及23例健康体检者(对照组),共96例作为研究对象。检测对所有患者的血脂水平、超敏C反应蛋白(CRP)含量、颈动脉内膜中层厚度(IMT),并对各组进行比较分析。结果甲减合并脑梗组的hs-CRP、TC、LDL-C、IMT明显高于对照组、甲减组及脑梗组(P<0.05),差异具有统计学意义。结论脑梗死合并亚临床甲减可加重动脉粥样硬化程度,临床干预脑梗死合并亚临床甲减非常必要。更多还原

【Abstract】 Objective To analyze the influence of subclinical hypothyroidism on carotid atherosclerosis of patients with cerebral infarction.Methods Ninety-six cases admitted in our hospital during 2011-2012were chosen as the research subjects,including 26patients with simple subclinical hypothyroidism(hypothyroidism group),25patients of simple cerebral infarction,22 cases of subclinical hypothyroidism combined with cerebral infarction(hypothyroidism merged with cerebral infarction group), and 23cases healthy check-up(control group).The blood lipid levels,hypersensitive c-reactive protein(hs-CRP)levels,carotid intima-media thickness(IMT)in all patients were detected and analyzed comparatively.Results The hs-CRP,TC,LDL-C and IMT of hypothyroidism combined with cerebral infarction group were significantly higher than those of the control group,hypothyroidism group and cerebral infarction group(P<0.05),the difference had a statistical significance.Conclusion Cerebral infarction combined with subclinical hypothyroidism can aggravate atherosclerosis,clinical intervention in these patients is very necessary.更多还原