【摘要】 目的研究CD90和血管内皮生长因子(VEGF)在肝细胞癌组织中的表达及其临床意义。方法利用免疫组化法检测33例肝细胞癌手术切除标本、25例癌旁组织标本和20例正常肝脏组织标本中CD90和VEGF的表达情况。结果肝细胞癌组织中CD90、VEGF的阳性表达率分别为72.73%和81.82%,高于癌旁组织(48.00%和52.00%)和正常肝脏组织(0.00%和45.00%)(P<0.05)。结论 CD90和VEGF表达与肝细胞癌的发生、发展关系密切。更多还原

【Abstract】 Objective To investigate the expressions and clinical significance of CD90 and vascular endothelial growth factor( VEGF) in the hepatocellular carcinoma. Methods Immunohistochemistry was used to detect the expressions of CD90 and VEGF in the 33 cases of hepatocellular carcinoma tissues,the 25 cases of paraneoplastic tissues and 20 cases of normal liver tissues. Results The positive expression rate of CD90 and VEGF in the hepatocellular carcinoma tissues( 72. 73% and 81. 82%) were higher than those in the paraneoplastic tissues( 48. 00%and 52. 00%) and the normal liver tissues( 0. 00% and 45. 00%)( P < 0. 05). Conclusion The expressions of CD90 and VEGF are closely related to the canceration and development of hepatocellular carcinoma.更多还原