【摘要】 目的对中药线叶菊[Filifolium sibiricum(L.)Kitam.]的化学成分进行分离鉴定。方法采用反复硅胶柱色谱、聚酰胺柱色谱、ODS反相柱色谱、重结晶等方法进行分离纯化,通过理化常数测定和波谱分析等手段鉴定其化学结构。结果分离得到6个单体化合物,5,7,4’-三羟基-6-甲氧基-二氢黄酮(5,7,4’-trihy-droxy-6-methoxy-flavanone,1),对羟基苯乙酮(4’-Hydroxyacetophenone,2),原儿茶酸甲酯(protoeatechuic-acid-methyl-ester,3),胡萝卜苷(daucosterol,4),L-2-O-甲基-手-肌醇(L-2-O-methyl-chiro-inositol,5)间苯三酚(phloroglucinol,6)。结论化合物1-6均为首次从线叶菊中分离得到。更多还原

【Abstract】 Purpose to study the chemical constituents of Filifolium Sibiricum by extraction,separation and identification.Method by using repeated silica gel column chromatography,polyamide column chromatography,ODS column chromatography ,recrystallization and other methods.Their structures were elucidated by their physicochemical properties and the spectral data analysis.Result six compounds were isolated and identified as 5,7,4’-trihy-droxy-6-methoxy-flavanone (1),4’-Hydroxyacetophenone (2),protoeatechuic-acid-methyl-ester (3),daucosterol (4),L-2-O-methyl-chiro-inositol(5) and phloroglucinol(6). Conclusion compound 1 to 6 are isolated fromthis plant for the first time.更多还原