【摘要】 目的探讨卒中后阻塞性睡眠呼吸暂停综合征患者相关危险因素,为临床诊断和防治提供理论依据。方法60名入组患者均登记相关危险因素、影像学检查,并行便携式多导睡眠监测,按照监测结果分为卒中合并OSAS组(CS-OSAS组)、脑卒中组(CS组)及OSAS组;并分析其影响因素。结果 OSAS发生率为58.3%;CS-OSAS组及OSAS组患者的AHI、ODI、SaO2<90%的时间、夜间平均SaO2、夜间最低SaO2与CS组患者比较差异有统计学意义(P<0.05);但CS-OSAS组及OSAS组之间比较无统计学意义(P>0.05)。CS-OSAS组合并高血压的比例高于CS组及OSAHS组患者,差异有统计学意义(P<0.05)。CS-OSAS组及OSAS组患者吸烟、饮酒、BMI、高血压病、糖尿病比例均高于CS组(P<0.05)。结论 CS-OSAS与OSAS患者存在明显的夜间低氧血症与呼吸暂停;吸烟、饮酒及BMI、高血压病、糖尿病可能是CS-OSAS发生的危险因素。更多还原

【Abstract】 Objective To investigate related risk factors of patients with poststroke obstructive sleep apnea syndrome( OSAS) in order to provide basis for diagnosis and treatment. Methods 60 patients were studied. All the patients completed image examinations and their basic information and related risk factors were registered. They were divided into 3 groups based on polysomnography: the cerebral stroke combined with OSAS group( CS-OSAS group),cerebral stroke group( CS group) and OSAS group. Clinical factors among the three groups were compared to identify the risk factors. Results The incidence of OSAS was 58. 3%. Compared with CS group,there was statistical differences in terms of AHI,ODI and,mean SaO2,MinSaO2< 90%,MinSaO2 in CS-OSAS group and OSAS group( P < 0. 05),but no differences between CS-OSAS group and OSAS group. There was a higher rate of complicated hypertension in CS-OSAS group than in CS group and OSAS group. The difference was significant( P < 0. 05). In comparison with CS group,the rates of smoking,alcohol,BMI,hypertension and diabetes in CS-OSAS group and OSAS group were significantly higher( P < 0. 05). Conclusion Apparently,hypopnea and sleep apnea exist in patients with CO-OSAS and OSAS. The rates of smoking,alcohol,BMI,hypertension and diabetes are often regarded as predictors of CSOSAS.更多还原