【摘要】 目的观察慢性阻塞性肺疾病(COPD)患者病情与甲状腺素变化的关系。方法分别检测47例COPD急性加重期患者急性加重期和缓解期血清甲状腺素(T4)、游离T4(FT4)、三碘甲状腺原氨酸(T3)、游离T3(FT3)及促甲状腺激素(TSH)含量,并与对照组比较。结果急性加重期时,COPD组中血清T3、FT3、T4均较对照组显著下降(P<0.01)。缓解期时,44例病情缓解者上述指标均明显上升(P<0.01),病情加重的3例无回升。结论血清甲状腺激素的变化与COPD患者病情严重程度相关,对COPD急性加重期患者的病情判断及预后具有一定的临床参考价值。更多还原

【Abstract】 Objective To observe the relationship between thyroid hormones and COPD patients’ conditions. Methods The serum levels of T3,T4,FT3,FT4and TSH of 47 patients with COPD were detected in acute exacerbation stage and remission stage. The results were compared with those of the controls. Results In the acute exacerbation stage,the serum levels of T3,FT3,T4 in patients with COPD were lower than those of the controls( P < 0. 01). In the remission stage,the above levels decreased significantly in 44 cases( P < 0. 01),but did not in 3 severe cases. Conclusion Changes of serum thyroid hormone are correlated with the severity of COPD patients,which has certain clinical values for the judgment and prognosis of the patients with COPD.更多还原