【摘要】 目的分析下肢动脉血栓形成患者动脉脉压差导致的血流动力学改变,探讨脉压差及其程度与动脉血栓形成的关系。方法分析因下肢缺血症状就诊的患者177例。所有患者均行股动脉切开取栓术或者行下肢动脉造影术、溶栓术及球囊扩张支架置入术。结果在177例患者中,动脉硬化闭塞症并血栓形成组患者的动脉脉压差均值与单纯动脉硬化闭塞症组比较差异有统计学意义。动脉硬化闭塞症并血栓形成患者脉压差明显高于单纯动脉硬化闭塞症者,动脉脉压差在血栓形成过程中有重要作用。177例患者中A组(脉压差>70mmHg)动脉血栓发生率为25.42%,B组(脉压差60~70mmHg)动脉血栓发生率为13.56%,C组(脉压差<60mmHg)动脉血栓发生率为6.78%,3组间差异有统计学意义。说明动脉硬化闭塞症患者随着动脉压差的增加,其病变动脉中血栓形成率明显增大。在血栓形成组中,脉压差的大小与血栓的长度无明显相关性。将所有研究对象按照脉压差>70mmHg和脉压差<70mmHg分为2组,去除性别这个混杂因素后,脉压差与动脉硬化闭塞后血栓形成高度相关。结论动脉硬化血管中动脉血栓的形成与动脉压差密切相关,并且动脉脉压差的程度与动脉血栓的形成直接相关。更多还原

【Abstract】 Objective To analyze hemodynamic changes leading arterial pulse pressure in patients with arterial thrombosis of lower extremity,discuss the relationship between pulse pressure and its degree of pulse pressure and arterial thrombus formation of lower extremity.Methods Analysis was made on the diagnosis results of 177 patients with lower extremity ischemia symptoms in the hospital.And,all the patients underwent femoral artery thrombectomy or lower extremity artery angiography,intra-arterial thrombolysis and balloon expandable or stent placement.Results In 177 patients,there was significant difference between the arterial pulse pressure average value in the patients of arteriosclerosis complicated with thrombosis and that of the patients of simple arteriosclerosis obliterans.The pulse pressure in patients with arterialsclerosis occlusion and thrombosis was significantly higher than that of patients with simple arteriosclerosis obliterans,arterial pulse pressure had an important role in the thrombus.One hundred and seventy-seven patients were divided into three groups.The incidence of arterial thrombosis was 25.42%in group A(> 70mmHg);13.56%group B(60-70mmHg) in patients with arterial thrombosis occurred;6.78%the patients with arterial thrombosis in group C(<60mmHg).The comparisons among three groups showed statistic significance,i.e.the different degrees of arterial had different effects on arterial thrombosis.As arterial pressure of patients with arteriosclerosis obliterans increased,the risk of thrombosis increased significantly in the arterial lesions.In thrombosis group,there were no significant correlation between the size of pulse pressure difference and the length of thrombus.The patients were divided into two groups,pulse pressure > 70mmHg,and pulse pressure < 70mmHg.By removing the confounding factor of gender,the pulse pressure was highly correlated with arterial occlusive thrombosis.Conclusion The thrombus formation in patients with atherosclerosis is close related with arterial pulse pressure,and the degree of arterial pulse pressure is directly related to arterial thrombosis.更多还原