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壳聚糖复合膜剂的制备及性能研究

Preparation and characteristics of composite chitosan membranes

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【作者】 关丽黄国程杨宝芸陈琳王秀珍

【Author】 GUAN Li;HUANG Guo-cheng;YANG Bao-yun;CHEN Lin;WANG Xiu-zhen;College of Pharmacy,Guangdong Pharmaceutical University;

【机构】 广东药学院药科学院

【摘要】 目的制备物理性能良好的壳聚糖(CTS)复合膜。方法将壳聚糖与明胶、可溶性淀粉、聚乙烯醇等3种不同材料共混成膜,使用甘油或聚乙二醇600(PEG600)为增塑剂,探讨所得膜的保湿性能、吸湿性能和水蒸气透过性能的变化规律。结果含量为20%的增塑剂均能达到较好的保湿性能和水蒸气透过率,且大多数情况下,甘油的增塑效果优于PEG。吸湿性能方面,CTS-淀粉复合膜与其它复合膜有些不同,随增塑剂含量增加,吸湿率有极大值出现。结论壳聚糖与其它水溶性高分子材料复合成膜后,其综合性能均有所提高。

【Abstract】 OBJECTIVE To prepare composite Chitosan( CTS) membranes with good physical properties. METHODS Composite membranes have been made blending chitosan with glutin,dissolvable starch,or polyvinyl alcohol( PVA). The physical properties of composite membranes,such as moisture retention,hygroscopicity and moisture permeability,have been researched,using glycerol or polyethylene glycol( PEG 600) as plasticizer. RESULTS Adding 20% of the plasticizer could achieve better moisture retention and moisture permeability. In most cases,the plasticizing effect of the glycerol was superior to PEG. Hygroscopicity of CTS-starch composite film was different from the other composite films. With the plasticizer content increasing,the hygroscopicity rate reached a maximum value. CONCLUSION The properties of Chitosan composite membranes have been improved.

【基金】 广东省科技计划项目,2012B031800228
  • 【文献出处】 海峡药学 ,Strait Pharmaceutical Journal , 编辑部邮箱 ,2014年01期
  • 【分类号】TQ460.6
  • 【被引频次】12
  • 【下载频次】414
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