【摘要】 目的探讨外科手术患者血清炎性指标的变化及其影响因素。方法选取2013年1~6月本院的372例手术患者为观察组,并以372名健康体检者为对照组,检测和比较两组的血清C-反应蛋白(CRP)、白细胞介素1(IL-1)、白细胞介素6(IL-6)和α肿瘤坏死因子(TNF-α)水平,并比较观察组中不同切口愈合程度、切口分类、抗生素使用情况、年龄段、性别、护理干预程度、手术时间、住院时间及住院条件者的血清检测水平。结果观察组血清CRP、IL-1、IL-6和TNF-α水平均高于对照组,且观察组中丙级切口、Ⅲ类切口、术后使用抗生素、一般护理干预、高龄、手术及住院时间较长者的检测水平均高于其他患者(P<0.05),但不同性别者之间则差异无统计学意义(P>0.05)。结论外科手术患者血清炎性指标明显更高,且受切口愈合程度、切口分类、抗生素使用情况、年龄段、护理干预程度、手术时间、住院时间及住院条件的影响较大。更多还原

【Abstract】 Objective To investigate the change state of serum inflammatory indexes of surgical patients and their influence factors. Methods 372 surgical patients in our hospital from January 2013 to June 2013 were the observation group, and 372 healthy persons were the control group,then the serum C-reactive protein(CRP), interleukin-1(IL-1), interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α) of two groups were detected and compared,and the serum detection levels of observation group with different incision healing degree, incision types, application situation of antibiotics, ages, gender, nursing intervention degree, operation time, hospitalization time and hospital conditions were compared too. Results The serum CRP, IL-1, IL-6 and TNF-α of observation group were all higher than those of control group, and the detection levels of patients with C grade incision, Ⅲ type incision, postoperative application of antibiotics, general nursing intervention, advanced age, longer operation time and hospitalization time were higher than those of other patients, there were significantly statistical differences(P<0.05), while the detection levels of patients with different gender had no statistically significant difference,(P>0.05). Conclusion The serum inflammatory indexes of surgical patients are obviously higher, and the influence of incision healing degree, incision types, application situation of antibiotics, ages, nursing intervention degree, operation time, hospitalization time and hospital conditions for the levels are great.更多还原