【摘要】 以酒石酸为拆分剂,从外消旋2-氨基丁醇中拆分出(D)-2-氨基丁醇和(L)-2-氨基丁醇。考察了不同的溶剂对2-氨基丁醇拆分的影响,最终选取了正丁醇作为拆分溶剂。并对反应时间,反应温度,溶剂体积对拆分的影响进行了考察。在最优条件下,D-2-氨基丁醇的总收率达到83.69%,旋光达到9.9°。更多还原

【Abstract】 D-2-amino-butanol and L-2-amino-butanol were separated from the DL-2-amino-butanol by the tartaric acid as the resolving agent.The effects of different solvent on the separation of 2-amino-butanol were investigated.Finally,butyl alcohol was chosen as the split solvent.The effects of reaction time,reaction temperature,and volume of solvent were also investigated.Under the optimized conditions,the final yield of D-2-amino-butanol was 83.69% and polarimetry was 9.9°.更多还原